Aging Changes In The Heart And Blood Vessels
The human aging process has a number of effects on the different bodily systems and their functionality.
As far as the cardiovascular system is concerned, aging causes restricted flow of blood in the lungs and also reduces the strength of the heartbeat.
- How Badly Are Your Arteries Hardening With Aging?
- What Happens To The Inner Layer Of Your Arteries As You Become Older?
- The Atherosclerotic Process
- The Battle is Not Over Yet
- The blood itself changes slightly with age.
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What Happens To The Inner Layer Of Your Arteries As You Become Older?
The lifetime of an endothelial cell is not infinite, and these cells, like those of your bowel, continuously multiply. However, with advancing age some of these specialized functions of the endothelial cell discussed above become blunted. The self-renewal process weakens.
The endothelial barrier becomes leaky. Signals to vascular smooth muscle cells to regulate their function become altered. Vascular smooth cells as if perceiving endothelial injury migrate to the intima, multiply there and produce collagen, a matrix protein, and other molecules. The addition of these cells and matrix within the sub endothelial space results in intimal thickening.
The intima of older arteries becomes a battleground where multiple reactions occur that are similar to a process of chronic injury. This battleground that occurs with aging provides fertile soil in which the seeds of a disease process called atherosclerosis flourish.
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